True but that just pushes the question one step back: why launch manned missions anywhere? Not really for scientific research, for a lot of things you'll get a better ROI elsewhere (and continually improving probe technology will cut into the manned advantages). Space colonisation is mostly ideological. Which I'm fine with, I just don't see enough people holding that ideology to pursue it at today's (and near future) costs.
OA Wish list:
- DNI
- Internal medical system
- A dormbot, because domestic chores suck!